Archibald E. Garrod Quote

All the more recent work on alkaptonuria has... strengthened the belief that the homogentisic acid excreted is derived from tyrosine, but why alkaptonuric individuals pass the benzene ring of their tyrosine unbroken and how and where the peculiar chemical change from tyrosine to homogentisic acid is brought about, remain unsolved problems.

Archibald E. Garrod

All the more recent work on alkaptonuria has... strengthened the belief that the homogentisic acid excreted is derived from tyrosine, but why alkaptonuric individuals pass the benzene ring of their tyrosine unbroken and how and where the peculiar chemical change from tyrosine to homogentisic acid is brought about, remain unsolved problems.

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About Archibald E. Garrod

Sir Archibald Edward Garrod (25 November 1857 – 28 March 1936) was an English physician who pioneered the field of inborn errors of metabolism. He also discovered alkaptonuria, understanding its inheritance. He served as Regius Professor of Medicine at the University of Oxford from 1920 to 1927.