If we recognize the power of entheogenic substances to open us to the universal truth and full dimension of human experience, and if we accept the role of the shaman as hierophant and psychopomp into this realm, as enacted for example by the Huichol mara'akame, we have to conclude that today in Western society we are deprived of two key resources for complete human growth. Young people, in their hunger for meaning, will still gravitate toward entheogens. The more experienced among us may try to ease their journey, but in the absence of qualified guides not all will benefit from their experience.