Michael Pollan Quote

This hall of epistemological mirrors was just one of the many challenges facing the researchers who wanted to bring LSD into the field of psychiatry and psychotherapy: psychedelic therapy could look more like shamanism or faith healing than medicine. Another challenge was the irrational exuberance that seemed to infect any researchers who got involved with LSD, an enthusiasm that might have improved the results of their experiments at the same time it fueled the skepticism of colleagues who remained psychedelic virgins. Yet a third challenge was how to fit psychedelics into the existing structures of science and psychiatry, if indeed that was possible. How do you do a controlled experiment with a psychedelic? How do you effectively blind your patients and clinicians or control for the powerful expectancy effect? When set and setting play such a big role in the patient’s experience, how can you hope to isolate a single variable or design a therapeutic application?

Michael Pollan

This hall of epistemological mirrors was just one of the many challenges facing the researchers who wanted to bring LSD into the field of psychiatry and psychotherapy: psychedelic therapy could look more like shamanism or faith healing than medicine. Another challenge was the irrational exuberance that seemed to infect any researchers who got involved with LSD, an enthusiasm that might have improved the results of their experiments at the same time it fueled the skepticism of colleagues who remained psychedelic virgins. Yet a third challenge was how to fit psychedelics into the existing structures of science and psychiatry, if indeed that was possible. How do you do a controlled experiment with a psychedelic? How do you effectively blind your patients and clinicians or control for the powerful expectancy effect? When set and setting play such a big role in the patient’s experience, how can you hope to isolate a single variable or design a therapeutic application?

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About Michael Pollan

Michael Kevin Pollan (; born February 6, 1955) is an American journalist who is a professor and the first Lewis K. Chan Arts Lecturer at Harvard University. Concurrently, he is the Knight Professor of Science and Environmental Journalism and the director of the Knight Program in Science and Environmental Journalism at the UC Berkeley Graduate School of Journalism where in 2020 he cofounded the UC Berkeley Center for the Science of Psychedelics, in which he leads the public-education program. Pollan is best known for his books that explore the socio-cultural impacts of food, such as The Botany of Desire and The Omnivore's Dilemma.