Despise (viradhana) of a Gnani [the enlightened one] creates hindrance in (acquiring right) Knowledge-Vision-Conduct (Gnan-Darshan-Charitra).
One is said to be enlightened with the Right Knowledge when his conduct is appropriate in any situation.
The one whose kashays, (inner anger, pride, deceit, greed) are gone is worthy of worship. The absence of inner intent of kashays is indeed Gnani!
The only difference between a happy and an unhappy person is that the former values what he has and the latter always values what he hasn't